A2B Adenosine Receptor Gene Deletion Attenuates Murine Colitis
نویسندگان
چکیده
منابع مشابه
Blockade of adenosine A2B receptors ameliorates murine colitis
BACKGROUND AND PURPOSE The adenosine 2B (A2B) receptor is the predominant adenosine receptor expressed in the colon. Acting through the A2B receptor, adenosine mediates chloride secretion, as well as fibronectin and interleukin (IL)-6 synthesis and secretion in intestinal epithelial cells. A2B receptor mRNA and protein expression are increased during human and murine colitis. However, the effec...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2008
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2008.05.049